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Korean Clinical Practice Guideline for Smoking Cessation Provided by the National Health Insurance Services
J Korean Soc Res Nicotine Tob 2023; 14(2): 41-48
Published online June 30, 2023
© 2023 The Korean Society for Research on Nicotine and Tobacco.

Yoo Bin Seo1, Yu-Jin Paek2*, Cheol Min Lee3*, Eon Sook Lee4, Hye Seon Kang5, Soo Young Kim6, Sungwon Roh7, Dong Won Park8, Yoo Suk An9, Sang-Ho Jo10; The Guideline Development Group for Developing the Korean Clinical Practice Guideline for Tobacco Cessation

1Department of Family Medicine, Wonkwang University Sanbon Hospital, Gunpo, 2Department of Family Medicine and Health Promotion Center, Hallym University Sacred Heart Hospital, Anyang, 3Department of Family Medicine, Seoul National University Hospital Healthcare System, Gangnam Center, Seoul, 4Department of Family Medicine, Inje University, Ilsan Paik Hospital, Goyang, 5Division of Pulmonary and Critical Care Medicine, Department of Internal Medicine, Bucheon St. Mary’s Hospital, Bucheon, 6Department of Family Medicine, Kangdong Sacred Heart Hospital, Hallym University Hospital, Seoul, 7Department of Psychiatry, Hanyang University Hospital, Seoul, 8Division of Pulmonary Medicine and Allergy, Department of Internal Medicine, Hanyang University College of Medicine, Seoul, 9Department of Psychiatry, Seoul National University Hospital, Seoul, 10Division of Cardiology, Department of Internal Medicine, Hallym University Sacred Heart, Anyang, Korea
Correspondence to: *백유진
한림대학교 성심병원 가정의학과
E-mail: noliaa@naver.com
ORCID: https://orcid.org/0000-0001-9573-8849
*이철민
서울대학교병원 강남센터 가정의학과
E-mail: bigbangx@snuh.org
ORCID: https://orcid.org/0000-0001-8652-4355
Received June 2, 2023; Revised June 16, 2023; Accepted June 22, 2023.
This is an Open-Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (https://creativecommons.org/licenses/by-nc/4.0/) which permits unrestricted non-commercial use, dis-tribution, and reproduction in any medium, provided the original work is properly cited.
 Abstract
Background: An evidence-based guideline was formed that addresses several questions regarding pharmacotherapy for smoking cessation among tobacco-dependent adults.
Methods: The multidisciplinary guideline panel selected seven clinical key questions and adopted the Grading of Recommendations Assessment, Development, and Evaluation (GRADE)-ADOLOPMENT methodology. The recommendations were verified through literature search and selection, evidence synthesis and evaluation, and the recommendation grade selection process.
Results: For smoking cessation in general population, our recommendation is to use varenicline rather than the nicotine patch or bupropion. We conditionally suggest combining varenicline with a nicotine patch instead of using varenicline alone. As for the duration of treatment, we recommend using extended-duration therapy (more than 12 weeks) rather than standard-duration therapy (6-12 weeks). For tobacco-dependent adults who are not yet ready to quit smoking, we recommend initiating treatment with varenicline rather than waiting for them to be ready. In special populations, for adults with a comorbid psychiatric condition, varenicline is preferred over the nicotine patch. Additionally, pharmacotherapy is strongly recommended for adults with chronic obstructive pulmonary disease.
Conclusion: Seven recommendations that focused on drug treatment for smoking cessation were developed. Moreover, the guideline panel expects that following these guidelines will increase the effectiveness of smoking cessation intervention.
Keywords : Smoking cessation; Practice guideline; Pharmacotherapy
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